Florence is about 200 miles from Venice.

I would suggest taking a train from Venice to Florence. Depending on the time of day, it will take more or less 2 hours and cost between $60 (economy) and $85 (comfort). The hotel is about a 20 minute walk from the station or reachable by a 5 minute taxi ride.

The other option is to rent a car in Venice and drive to Florence. It is a beautiful drive and involves mostly super highway. BUT, driving in Italy is not for the feint of heart and, at some time, you will need to leave the highway and navigate the streets of the city.

Many thanks Mary Ann