Barbara, sounds like a great vacation plan. Loads of choices for where to go, so to help you get started, here are a couple of features we've published on Away.com. One is an eight-day itinerary that takes in Yosemite and Napa/Sonoma, so you could crib some ideas from that: http://bit.ly/TbzL8r

We also have a piece on northern Napa vineyard tours here: http://away.com/features/northern-napa-vineyard-tours.html, including ideas for a few places to stay. Lastly, here's a link to a gallery of images from Sonoma to inspire more wanderlust! http://bit.ly/VsbF8f

San Fran speaks for itself: dim-sum in Chinatown, Fisherman's Wharf, trip across the Golden Gate Bridge to the Marin headlands, Alcatraz, San Francisco Museum of Modern Art, de Young museum... have fun!